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Machine Learning Inference of Continuous Single-Cell State Transitions during Myoblast Differentiation and Fusion



Investigators combined live-cell imaging and machine learning to monitor ERK1/2-inhibited primary murine skeletal muscle precursor cells, that transitioned rapidly and robustly from proliferating myoblasts to post-mitotic myocytes and then fuse, forming multinucleated myotubes.

[Molecular Systems Biology]

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